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Agilent

BioTek 405 TS

Short product description
The gold standard in microplate washing with clog detection

Information

The 405 TS Microplate Washer is the gold standard in microplate washing. It features the patented Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifold. The 405 TS is the first self-checking, self-maintaining microplate washer available!

Cell-based assays and microsphere-based assays are easily run with the 405 TS’s unique set of available features and modules for gentle washing vacuum filtration and biomagnetic separation.

• Patented Verify™ clog detection technology and Ultrasonic Advantage™
• High resolution, advanced touch screen User Interface
• USB flash drive ports for convenient file transfer and storage
• Optimized for loosely adherent monolayers: low flow rates, angled dispensing
  • Configurations

    Part #
    384-well
    96-well
    Optimized Cell Washing
    4-Buffer Switching
    Ultrasonic Advantage
    Verify™ technology
    Biomagnetic Separation**
    Vacuum Filtration**
    405TSHT
     *
    405TSHTV
     *
    405TSU
    405TSUV
     
    405TSUS
    405TSUSQ
     
    405TSUVS
    405TSUVSQ
     
    405TSR
    405TSRV
    405TSRS
    405TSRSQ
    405TSRVS
    405TSRVSQ

    * 96-well washing available with optional manifold PN 1170010, sold separately
    ** With available accessory module sold separately

    405™ TS Microplate Washer Configurations
    Feature Design
    HT Faster 384-well microplate washing 192-tube (16 x 12) manifold
    Dual-Action™
    HT Includes Ultrasonic Advantage
    V Automated Internal 4-Buffer Switching
    S Ultrasonic Advantage™ Built-in ultrasonic cleaner for manifold self-maintenance
    U 96-/384-well microplate washing 96-tube (8 x 12) manifold
    Dual-Action™
    R 96-well microplate washing 96-tube (8 x 12) manifold
    Q Verify™ technology Built-in clog detection for dispense and aspirate tubes
  • specifications

    GENERAL
    Microplate types 96- and 384-well
    Low profile and standard height
    Solid and filter bottom (option)
    Filter pore sizes from 0.45 µm to 1.2 µm
    Onboard software Create, edit or run multiple protocols
    Software (computer control) LHC2 pc software
    LHC2 Secure for 21 CFR Part 11 compliance (option)
    SiLA Compliant driver (option)
    Separation Biomagnetic separation, vacuum filtration (optional)
    Shaking Programmable up to 60 minutes
    Slow, medium, fast or variable
    Soaking Programmable up to 60 minutes
    Ultrasonic Advantage™ Yes (option)
    Verify™ clog detection Yes (option)
    Automation BioStack and 3rd party automation compatible
    BioSpa 8 Automated Incubator compatible
    WASHING
    Manifold types 96-well washing: 96-tube manifold – straight dispense tubes
    96- and 384-well washing: 96-tube Dual-Action manifold – 20° angled dispense tubes
    384-well washing (fast): 192-tube Dual-Action manifold – 7° angled dispense tubes
    Volume range 25 – 3,000 µL/well, in 1 µL increments
    Wash cycles 1 – 250
    Buffer/reagent selection Auto switching (internal) for up to 4 buffers (option)
    Supply bottle 4 L or 10 L (optional)
    Dispense precision <3% CV: 300 µL/well (96-well washing)
    <4% CV: 80 µL/well (384-well washing)
    Residual volume < 2 µL/well (96- & 384-well plates)
    96-tube manifold for 96 wells; 192-tube for 384 wells
    Wash speed 96-wells, 300 µL/well, 3 cycles; <30 seconds
    384-wells,100 µL/well, 3 cycles: <80 seconds
    384-wells, 400 µL/well, 1 cycle: <20 seconds
    Flow rates High flow to low flow
    Optimized rates for cell assays
    Sterilization Chemical
    Vacuum filtration Selectable: Approximate final at 30 seconds:
    Lowest: -38 mmHg
    Low: -113 mmHg
    Medium: -200 mmHg
    High: -390 mmHg
    Highest: -506 mmHg
    Vacuum filtration time range: 5 to 999 seconds
    PHYSICAL CHARACTERISTICS
    Power 100 – 240 Volts AC. 50/60 Hz
    Dimensions 14″ W x 17″ D x 10″ H
    (35.6 x 43.2 x 25.4 cm)
    Weight With internal buffer switching – 36 lbs (16.5 kg)
    Without – 30 lbs (13.5 kg)
    REGULATORY
    Regulatory CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available.
  • Software

    The 405 TS has extensive onboard software, accessed through the convenient touchscreen interface. Program all aspects of the system’s wash and maintenance parameters, quickly and easily and store them onboard for routine use.

    LHC
    LHC Software allows computer-based programming of multi-step processes and it is used for integrating BioTek’s multi-mode washer dispensers, washers and dispensers into robotic systems. You can operate the system under computer control via LHC, or create protocols in LHC and download to the instrument for recall and execution.

    LHC Secure software
    LHC Secure software offers features to facilitate compliance to FDA directive 21 CFR Part 11
    with computer control of BioTek’s Multi-Mode Washer Dispensers, Washers and Dispensers.

    LHC SiLA
    LHC SiLA software driver enables BioTek washer and dispenser integration into SiLA compliant automated systems. Includes LHC software for computer control and third party integration of BioTek’s Multi-Mode Washer Dispensers, Washers and Dispensers.

  • Features

    Patented Verify™ clog detection technology and Ultrasonic Advantage™
    Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifolds.

    High resolution, advanced touch screen User Interface
    405 TS features high resolution touch screen user interface for intuitive and flexible programming of 96- and 384-well microplate wash protocols. The extensive onboard software seamlessly guides users through protocol development, instrument maintenance and operation.

    USB flash drive ports for convenient file transfer and storage
    Two USB ports on the 405 TS enable convenient file transfer, storage and operation.

    Optimized for loosely adherent monolayers: low flow rates, angled dispensing
    The 405 TS can process sensitive cell-based assays with its angled dispense tubes and adjustable flow rates. The Dual-Action manifold and carrier offer X-Y-Z adjustment, perfect for optimizing plate positioning and residual removal for cell-based and other assays.

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