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BioTek 405 TS
Information
The 405 TS Microplate Washer is the gold standard in microplate washing. It features the patented Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifold. The 405 TS is the first self-checking, self-maintaining microplate washer available!
Cell-based assays and microsphere-based assays are easily run with the 405 TS’s unique set of available features and modules for gentle washing vacuum filtration and biomagnetic separation.
• High resolution, advanced touch screen User Interface
• USB flash drive ports for convenient file transfer and storage
• Optimized for loosely adherent monolayers: low flow rates, angled dispensing
Configurations
Part # 384-well 96-well Optimized Cell Washing 4-Buffer Switching Ultrasonic Advantage Verify™ technology Biomagnetic Separation** Vacuum Filtration** 405TSHT• *• • • 405TSHTV• *• • • • 405TSU• • • • • 405TSUV• • • • • • 405TSUS• • • • • • 405TSUSQ• • • • • • • 405TSUVS• • • • • • • 405TSUVSQ• • • • • • • • 405TSR• • • 405TSRV• • • • 405TSRS• • • • 405TSRSQ• • • • • 405TSRVS• • • • • 405TSRVSQ• • • • • • * 96-well washing available with optional manifold PN 1170010, sold separately ** With available accessory module sold separately405™ TS Microplate Washer Configurations Feature Design HT Faster 384-well microplate washing 192-tube (16 x 12) manifold Dual-Action™ HT Includes Ultrasonic Advantage V Automated Internal 4-Buffer Switching S Ultrasonic Advantage™ Built-in ultrasonic cleaner for manifold self-maintenance U 96-/384-well microplate washing 96-tube (8 x 12) manifold Dual-Action™ R 96-well microplate washing 96-tube (8 x 12) manifold Q Verify™ technology Built-in clog detection for dispense and aspirate tubes specifications
GENERAL Microplate types 96- and 384-well Low profile and standard height Solid and filter bottom (option) Filter pore sizes from 0.45 µm to 1.2 µm Onboard software Create, edit or run multiple protocols Software (computer control) LHC2 pc software LHC2 Secure for 21 CFR Part 11 compliance (option) SiLA Compliant driver (option) Separation Biomagnetic separation, vacuum filtration (optional) Shaking Programmable up to 60 minutes Slow, medium, fast or variable Soaking Programmable up to 60 minutes Ultrasonic Advantage™ Yes (option) Verify™ clog detection Yes (option) Automation BioStack and 3rd party automation compatible BioSpa 8 Automated Incubator compatible WASHING Manifold types 96-well washing: 96-tube manifold – straight dispense tubes 96- and 384-well washing: 96-tube Dual-Action manifold – 20° angled dispense tubes 384-well washing (fast): 192-tube Dual-Action manifold – 7° angled dispense tubes Volume range 25 – 3,000 µL/well, in 1 µL increments Wash cycles 1 – 250 Buffer/reagent selection Auto switching (internal) for up to 4 buffers (option) Supply bottle 4 L or 10 L (optional) Dispense precision <3% CV: 300 µL/well (96-well washing) <4% CV: 80 µL/well (384-well washing) Residual volume < 2 µL/well (96- & 384-well plates) 96-tube manifold for 96 wells; 192-tube for 384 wells Wash speed 96-wells, 300 µL/well, 3 cycles; <30 seconds 384-wells,100 µL/well, 3 cycles: <80 seconds 384-wells, 400 µL/well, 1 cycle: <20 seconds Flow rates High flow to low flow Optimized rates for cell assays Sterilization Chemical Vacuum filtration Selectable: Approximate final at 30 seconds: Lowest: -38 mmHg Low: -113 mmHg Medium: -200 mmHg High: -390 mmHg Highest: -506 mmHg Vacuum filtration time range: 5 to 999 seconds PHYSICAL CHARACTERISTICS Power 100 – 240 Volts AC. 50/60 Hz Dimensions 14″ W x 17″ D x 10″ H (35.6 x 43.2 x 25.4 cm) Weight With internal buffer switching – 36 lbs (16.5 kg) Without – 30 lbs (13.5 kg) REGULATORY Regulatory CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available. Software
The 405 TS has extensive onboard software, accessed through the convenient touchscreen interface. Program all aspects of the system’s wash and maintenance parameters, quickly and easily and store them onboard for routine use.
LHC
LHC Software allows computer-based programming of multi-step processes and it is used for integrating BioTek’s multi-mode washer dispensers, washers and dispensers into robotic systems. You can operate the system under computer control via LHC, or create protocols in LHC and download to the instrument for recall and execution.LHC Secure software
LHC Secure software offers features to facilitate compliance to FDA directive 21 CFR Part 11
with computer control of BioTek’s Multi-Mode Washer Dispensers, Washers and Dispensers.LHC SiLA
LHC SiLA software driver enables BioTek washer and dispenser integration into SiLA compliant automated systems. Includes LHC software for computer control and third party integration of BioTek’s Multi-Mode Washer Dispensers, Washers and Dispensers.Features
Patented Verify™ clog detection technology and Ultrasonic Advantage™
Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifolds.High resolution, advanced touch screen User Interface
405 TS features high resolution touch screen user interface for intuitive and flexible programming of 96- and 384-well microplate wash protocols. The extensive onboard software seamlessly guides users through protocol development, instrument maintenance and operation.USB flash drive ports for convenient file transfer and storage
Two USB ports on the 405 TS enable convenient file transfer, storage and operation.Optimized for loosely adherent monolayers: low flow rates, angled dispensing
The 405 TS can process sensitive cell-based assays with its angled dispense tubes and adjustable flow rates. The Dual-Action manifold and carrier offer X-Y-Z adjustment, perfect for optimizing plate positioning and residual removal for cell-based and other assays.
Brochures
Application notes
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