The Liberty Lite™ Microwave Peptide Synthesizer is an entry level option for the globally recognized
Liberty Blue™ technology. The Liberty Lite provides advantages over existing peptide synthesizers
with it’s patented use of microwave irradiation during both the deprotection and coupling steps
(15 minute cycle times), in situ temperature control, Flex-Add™ delivery system, and efficient
solvent usage. Additionally, the system can be upgraded at any time to a complete Liberty Blue system.
Don’t be limited by fixed sample loops for reagent addition! CEM’s patented Flex-Add™ technology enables a wider range of addition volumes than any other synthesizer. This factory calibrated feature allows infinitely variable volume additions for all amino acid and activator deliveries, and requires no customer calibration after system installation.
In-Situ Fiber Optic Temperature Control
Fast heating requires fast and accurate temperature measurement to prevent thermal overshoot; in-situ temperature measurement provides the most responsive, reliable, and accurate feedback on reaction conditions. The fiber optic probe on the Liberty Lite provides this type of measurement capability and avoids the lag time associated with external IR or thermocouple controls and eliminates the need for routine calibration.
The Microwave Advantage
Microwave energy brings more to peptide synthesis than a rapid change in temperature. Combined with microwave transparent reaction vessels, your reaction, not the vessel, is heated with a uniform, single mode energy distribution. Rapid kinetic movement caused by microwave energy accelerates the reaction and reduces aggregation. The Discover® is the only microwave capable of applying microwave energy to both the deprotection and coupling steps of solid phase peptide synthesis.
|Synthesis Scale||0.005-5 mmol|
|Reaction Vessel Sizes||30- and 125-mL|
|Activation Method||in situ standard activators|
|Amino Acid Reagents||20|
|External Bottle Positions||2|
|Temperature Measurement||in situ fiber optic|
|Fluid Measurement||Flex-Add - amino acids, activator, activator base, Timed delivery - main wash, deprotection|
|Agitation||Programmable inert gas bubbling|
|Waste Container||1 L reservoir with overflow detection Larger sizes available|
|Controller||Laptop with wireless option standard|
|Optional Features||Cleavage module|
|Reports||Printable .pdf file for each method created Log created during each run of every step performed|
|Power||120V/60Hz or 240V/50Hz|
|Dimensions||20”W x 18”D x 30”H (51cm x 46 cm x 76 cm)|
|License||The purchase of this instrument includes a grant of limited, non-transferrable, license to utilize this instrument for microwave peptide synthesis using microwave energy for both the coupling and deprotection steps|