BioTek 405TS

Microplate Washer

Overview

The 405 TS Microplate Washer is the gold standard in microplate washing. It features the patented Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifold. The 405 TS is the first self-checking, self-maintaining microplate washer available! Cell-based assays and microsphere-based assays are easily run with the 405 TS's unique set of available features and modules for gentle washing vacuum filtration and biomagnetic separation.

• Patented Verify™ clog detection technology and Ultrasonic Advantage™
• High resolution, advanced touch screen User Interface
• USB flash drive ports for convenient file transfer and storage
• Optimized for loosely adherent monolayers: low flow rates, angled dispensing

405TS Microplate Washer product video.

BioTek 405TS Microplate Washer Details



Patented Verify™ clog detection technology and Ultrasonic Advantage™
Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifolds.

High resolution, advanced touch screen User Interface
405 TS features high resolution touch screen user interface for intuitive and flexible programming of 96- and 384-well microplate wash protocols. The extensive onboard software seamlessly guides users through protocol development, instrument maintenance and operation.

USB flash drive ports for convenient file transfer and storage
Two USB ports on the 405 TS enable convenient file transfer, storage and operation.

Optimized for loosely adherent monolayers: low flow rates, angled dispensing
The 405 TS can process sensitive cell-based assays with its angled dispense tubes and adjustable flow rates. The Dual-Action manifold and carrier offer X-Y-Z adjustment, perfect for optimizing plate positioning and residual removal for cell-based and other assays.
GENERAL
Microplate types 96- and 384-well
Low profile and standard height 
Solid and filter bottom (option)
Filter pore sizes from 0.45 µm to 1.2 µm
Onboard software Create, edit or run multiple protocols
Software (computer control) LHC2 pc software
LHC2 Secure for 21 CFR Part 11 compliance (option)
SiLA Compliant driver (option)
Separation Biomagnetic separation, vacuum filtration (optional)
Shaking Programmable up to 60 minutes
Slow, medium, fast or variable
Soaking Programmable up to 60 minutes
Ultrasonic Advantage™ Yes (option)
Verify™ clog detection Yes (option)
Automation BioStack and 3rd party automation compatible
BioSpa 8 Automated Incubator compatible
WASHING
Manifold types 96-well washing: 96-tube manifold - straight dispense tubes
96- and 384-well washing: 96-tube Dual-Action manifold - 20° angled dispense tubes
384-well washing (fast): 192-tube Dual-Action manifold - 7° angled dispense tubes
Volume range 25 - 3,000 µL/well, in 1 µL increments
Wash cycles 1 - 250
Buffer/reagent selection Auto switching (internal) for up to 4 buffers (option)
Supply bottle 4 L or 10 L (optional)
Dispense precision <3% CV: 300 µL/well (96-well washing)
<4% CV: 80 µL/well (384-well washing)
Residual volume < 2 µL/well (96- & 384-well plates)
96-tube manifold for 96 wells; 192-tube for 384 wells
Wash speed 96-wells, 300 µL/well, 3 cycles; <30 seconds
384-wells,100 µL/well, 3 cycles: <80 seconds 
384-wells, 400 µL/well, 1 cycle: <20 seconds
Flow rates High flow to low flow 
Optimized rates for cell assays
Sterilization Chemical
Vacuum filtration Selectable: Approximate final at 30 seconds:
Lowest: -38 mmHg
Low: -113 mmHg
Medium: -200 mmHg
High: -390 mmHg
Highest: -506 mmHg 
 
Vacuum filtration time range: 5 to 999 seconds
PHYSICAL CHARACTERISTICS
Power 100 - 240 Volts AC. 50/60 Hz
Dimensions 14" W x 17" D x 10" H
(35.6 x 43.2 x 25.4 cm)
Weight With internal buffer switching - 36 lbs (16.5 kg)
Without - 30 lbs (13.5 kg)
REGULATORY
Regulatory CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available.
Part #
384-well
96-well
Optimized Cell Washing
4-Buffer Switching
Ultrasonic Advantage
Verify™ technology
Biomagnetic Separation**
Vacuum Filtration**
405TSHT
 *
   
 
405TSHTV
 *
 
 
405TSU
     
405TSUV
 
 
 
405TSUS
 
 
405TSUSQ
 
 
405TSUVS
 
405TSUVSQ
 
405TSR
 
 
 
   
405TSRV
 
 
   
405TSRS
 
 
 
 
405TSRSQ
 
   
405TSRVS
 
 
 
405TSRVSQ
 
 
* 96-well washing available with optional manifold PN 1170010, sold separately

** With available accessory module sold separately




405™ TS Microplate Washer Configurations
  Feature Design
HT Faster 384-well microplate washing 192-tube (16 x 12) manifold
Dual-Action™
HT Includes Ultrasonic Advantage
V Automated Internal 4-Buffer Switching  
S Ultrasonic Advantage™ Built-in ultrasonic cleaner for manifold self-maintenance
U 96-/384-well microplate washing 96-tube (8 x 12) manifold
Dual-Action™
R 96-well microplate washing 96-tube (8 x 12) manifold
Q Verify™ technology Built-in clog detection for dispense and aspirate tubes
LHC


The 405 TS has extensive onboard software, accessed through the convenient touchscreen interface. Program all aspects of the system’s wash and maintenance parameters, quickly and easily and store them onboard for routine use.

LHC
LHC Software allows computer-based programming of multi-step processes and it is used for integrating BioTek’s multi-mode washer dispensers, washers and dispensers into robotic systems. You can operate the system under computer control via LHC, or create protocols in LHC and download to the instrument for recall and execution.

LHC Secure software
LHC Secure software offers features to facilitate compliance to FDA directive 21 CFR Part 11
with computer control of BioTek’s Multi-Mode Washer Dispensers, Washers and Dispensers.

LHC SiLA
LHC SiLA software driver enables BioTek washer and dispenser integration into SiLA compliant automated systems. Includes LHC software for computer control and third party integration of BioTek’s Multi-Mode Washer Dispensers, Washers and Dispensers.